Learn about the latest medical breakthroughs by participating in webinars on topics surrounding disease, prevention and treatment in accordance with the latest research in health and medicine. Updates encompass a biological, psychological and sociological understanding of health.
The nervous system of social species has evolved to perceive and evaluate signals within a social context. Social information therefore must impact how the brain processes information, yet l...
Current cancer management follows a multipronged approach that include surgery, radiation, and chemotherapy. There is a pressing need for a platform technology to provide precision chemother...
Comprehensive genomic profiling in clinical research studies helps to detect clinically relevant cancer driver mutations using low amount of tumor tissues within several days. Recent studies...
High volume clinical MS proteomic evaluation of plasma samples enriched for exosomes offering a real-time and non-invasive perspective of changing maternal and fetal tissues....
In this project, we optimized a high-throughput fluorescent-based assay to assess transporter activity by measuring uptake of the substrate, ASP+ 4-(4-(dimethylamino)styryl)-N-methylpyridi...
In the United States, prostate cancer (PCa) is the second-leading cause of cancer death in men. Multiple observations indicate the link between prostate carcinogenesis, stress of endoplasmi...
Uterine leiomyosarcoma (uLMS) is a rare aggressive sarcoma of the smooth muscle layer of the uterus manifested in high local recurrence and metastatic rate. Currently, effective treatment of...
Jeff Borgia, Ph.D. is the Director of the Rush Cancer Center Biorepository, where he oversees the collection and annotation of patient specimens in support of ongoing translational research...
Analysis of community wastewater has been shown to be an effective method for tracking the prevalence of SARS-COV-2. Our group has developed techniques for sequencing a portion of the SARS-C...
Preclinical research and development are the cornerstone of modern drug discovery. A variety of biological systems including in vitro, 3D cultures, and organoids are essential tools, with ul...
The microenvironment of many solid tumors impedes many immunotherapeutic treatments by inhibiting the effector functions of many classes of anti-tumor immune cells, including effector T cell...
The ultimate promise of tumor immunotherapy is dependent on the generation of effective immunity against cancer, including CD4 and CD8 T cell responses. However, activating T cells in cancer...
AAV peptide display libraries allow for the generation of novel variants capable of high-level transduction. We previously described an AAV peptide display library combined with a sensitive...
I will discuss and present data and viewpoints so discuss the current situation with THC Lab shopping, it’s impact on the industry from growers through labs to end-users, how we got he...
Immunotherapy has changed the landscape of oncology, improving survival rates for many patients across a variety of malignancies. Two antibody-based immunotherapies, immune checkpoint inhibi...
There are currently several different FDA approved radiopharmaceuticals being used in both large academic and small practice settings to accurately stage and identify local and metastatic pr...
Since its discovery in late 2019 the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created a global pandemic of coronavirus disease 2019 (COVID-19). As of July of 2022, mo...
Mass spectrometry-based proteomics is a powerful technique for the analyses of thousands of proteins, fueling biomarker research and drug discovery. With the rich complex data from each prec...
Lateral flow assays (LFA) are simple diagnostic tools that can be used to detect a variety of biomolecules that include biomarkers, pathogens, and environmental contaminants. Many industries...
Self-removing tags can be used for simple and effective purification of recombinant proteins and peptides. The key component of these tags is an intein, which is a protein element with the a...
Prompt and early diagnosis of sexually transmitted infections (STIs) is important to enable appropriate treatment and help prevent further transmission....
Over the last decade we have witnessed tremendous advances in our understanding of the underlying molecular alterations in human cancer. This has stimulated excitement for our ability to deve...
November 13, 2020 5:00 PM PST | November 14, 2020 9:00 AM SGT
Ensuring that clinical tests are not affected by tumor heterogeneity requires a sampling methodology that captures the genomic, proteomic, and cellular diversity of entire solid tumors. Howe...
Mouse models have been essential for establishing the role of the T cells in anti-tumor responses, but they have limited utility in translational studies for the testing of candidate therape...
Though AsCas12a fills a crucial gap in the current genome editing toolbox, it exhibits relatively poor editing efficiency, restricting its overall utility. In collaboration with Integrated D...
The nervous system of social species has evolved to perceive and evaluate signals within a social context. Social information therefore must impact how the brain processes information, yet l...
