Advances in clinical laboratory techniques and molecular analysis are reshaping our approach to therapy and diagnosis. Explore emerging diagnostic technology and the latest insights in the microbial community in these webinars.
Long read Structural Variation calling remains a challenging but highly accurate way to identify complex genomic alterations. To address this challenge, we developed Sniffles2, a successor t...
The nuclear proliferation biomarker Ki-67 has multiple potential roles in breast and other cancers, both as a prognostic but also predictive marker. However, several studies have shown that...
Pregnancy represents a time of rapid bodily change, which include physical proportions, physiology and responsibility. Arguably, nothing during these times changes more than the requirement a...
Cervical cancer is the 4th most common cancer worldwide with 528,000 new cases and 266,000 deaths every year. It is also the only cancer 100% preventable. It has been extensively proved, that...
Screening for cervical cancer represents one of the greatest successes achieved in disease prevention. Cytology has been central to cervical cancer screening programs for over 50 years and ha...
In the event of a radiological or nuclear disaster, there will be a need for therapies that can mitigate the acute hematopoietic and gastrointestinal (GI) radiation syndromes expected to dev...
The integration of next-generation sequencing (NGS) tests into clinical laboratory practice across medical disciplines provides medically actionable data that in some cases are not otherwise...
With the exception of the Microbiome Quality Control (MBQC), very little has been published on best practices and reference standards for microbiome and metagenomic studies. As evidenced by r...
Patient laboratory test results are significantly over-represented in electronic medical records, but significantly under-utilized in research. An important application of laboratory data is...
In 2012, Consumers Reports and the American Board of Internal Medicine Foundation launched the Choosing Wisely campaign. This initiative, which attracts media attention, assists physicians, n...
Random drug testing is used as a preventive and detection tool for drug or alcohol use, and medication compliance in the monitoring of regulatory and treatment compliance monitoring. Urine sc...
The opioid crisis has put significant strain on the healthcare system and resources, including the clinical laboratory which has seen significant increases in requests for urine drug screeni...
Second and third generations of PTH immunoassays currently available on the market demonstrate significant variability with up to 4.2 fold difference in measurements depending on the method u...
Burn patients are at risk for organ dysfunction secondary to “burn shock” and sepsis. The initial 24 hours following major burn injury presents with significant hypotension due to...
Transcriptomics represents a critical discipline in cancer research, enabling comprehensive mapping of gene expression profiles and the identification of fusion genes implicated in tumor dev...
Background and aim: Multiplexing of biomarker panels by microsphere-based technologies are robust and cost-effective methods. The QuantiGene™ Plex Assay (ThermoFisher Scientific) platf...
Histone post-translational modifications (PTMs) play pivotal roles in chromatin dynamics and function, with alterations in the healthy profile associated with diverse human pathologies. The...
CRISPR-chip combines two powerful technologies ,CRISPR and Graphene, for rapid detection of nucleic acids. This talk will focus on design and fabrication of CRISPR-chip and its potential util...
Next-generation sequencing is expected to take molecular diagnostics to the next level with the capability to perform deep analysis of genetic information that leads to targeted therapies per...
Lab-on-a-chip platforms enable advanced processing, manipulation, and analysis of biological samples in miniaturized fluidic devices. Despite the numerous advantages, such as lower reagent a...
Breast cancer is the most frequently occurring form of cancer in women. While 5-year survival rates for localized disease approach 99%, cases of advanced breast cancer have a much poorer pro...
Many direct immunoassays in use today for testosterone analysis are little better than a guess at the low levels that are sometimes required. This has led many clinical societies to adv...
Anchored Protein Kinase-A (PKA) bound to A-Kinase Anchoring Protein (AKAP) mediates the effects of localized increases in cAMP in defined subcellular microdomains and retains the specificity...
Streptococcus pyogenes or Group A Streptococcus (GAS) is a pathogenic bacteria that causes both invasive and non-invasive infections resulting in mild to severe life-threatening disease.L...
A recent clinical trial of the AR inhibitor enzalutamide in patients with TNBC included an exploratory endpoint using RNA sequencing to identify a genomic signature of patients likely to resp...
While clinical microbiology laboratories are pivotal in the identification and handling of infectious diseases, the microbiology lab environment is rapidly changing. Conventional testing met...
Long read Structural Variation calling remains a challenging but highly accurate way to identify complex genomic alterations. To address this challenge, we developed Sniffles2, a successor t...
