Human Pancreatic Amylase is a secreted enzyme that is present in saliva and pancreatic secretions in the form of alpha-amylase with 496 amino acids and 56 kDa. Salivary alpha-amylase catalyses the hydrolysis of 1,4-alpha-glycosidic bonds of starch into disaccharide maltose, trisaccharide maltotriose, and small dextrins. Pancreatic alpha-amylase continues the hydrolysis of starch into disaccharides and trisaccharides which are converted by alpha-glucosidases to absorbable glucose, fructose, and galactose in the small intestine. The serum amylase concentration is increased in acute pancreatitis, and ovarian tumors. By retardation of carbohydrate digestion, the amylase inhibitor has anti-obesity and anti-diabetes effects and can control postprandial hyperglycemia in type 2 diabetes. Salivary alpha-amylase has been proposed as a stress biomarker in autonomic/sympathetic nervous system.