Prevent Prostate Cancer with Broccoli and Antimalarial Medication

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prostatecancercellsA new study from the University of Pittsburgh suggests a combination of a phytochemical in broccoli and a malaria drug could lower prostate cancer rates.

Cruciferous vegetables such as broccoli, watercress, and cabbage have the phytochemical sulforaphane, which is thought to help lower prostate cancer risk. When tested, researchers found that it works to prevent early-stage but not late-stage prostate cancer, which is thought to be due to autophagy, a cellular mechanism that limits ability of drugs to destroy cancer.

Choroquine is an antimalarial drug that inhibits autophagy. So, when these two chemicals were given to mice predisposed to prostate cancer, 12% developed late-stage prostate cancer as opposed to half of the control group. These findings are very promising but more research and clinical testing is needed before any attempt of combining these in humans is possible.

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