Genetics and Genomics

Inhibiting specific enzymes involved with the genetic machinery aiding in brain development could cause Autism. Researchers at the Neuroscience Center, University of North Carolina have shown the importance of topoisomerase dysfunction in brain, and specifically synapse, development. Topoisomerases are in all human cells and help to untangle tightly wound or overwound DNA, which can interfere with...

Everyone has a diverse population of microbes living on their skin, known as the skin microbiome. Prior research done by University of Pennsylvania researchers highlighted the diversity of bacteria living on the skin with DNA-based sequence analysis of the bacterial genomes. Now, the group has been able to include the immune system and how it influences...